Publications
PI's PhD and Postdoc Publications:
1. Chopra, Pradeep; Yadavalli, Tejabhiram*; Palmieri, Francesco; Jongkees, Seino AK; Unione, Luca; Shukla, Deepak; Boons, Geert-Jan; Synthetic Heparanase Inhibitors Can Prevent Herpes Simplex Viral Spread, Angewandte Chemie, e202309838, (Accepted) 2023 Co-First Author
2. Ali, Marwan; Shah, Dhara; Coursey, Terry G; Lee, Sang Min; Balasubramaniam, Arun; Yadavalli, Tejabhiram; Edward, Deepak; Son, Kyung-No; Shukla, Deepak; Aakalu, Vinay Kumar; Modulation of ocular surface desiccation in a murine model by histatin-5 application, The Ocular Surface, 27, 30-37, 2023
3. Suryawanshi, Rahul K; Patil, Chandrashekhar D; Agelidis, Alex; Koganti, Raghuram; Yadavalli, Tejabhiram; Ames, Joshua M; Borase, Hemant; Shukla, Deepak; Pathophysiology of reinfection by exogenous HSV-1 is driven by heparanase dysfunction, Science Advances, 9, 17, eadf3977, 2023
4. Koganti, Raghuram; Yadavalli, Tejabhiram*; Shukla, Deepak; In vitro protocol for the optimal induction of inflammation in human monocyte cell lines, STAR protocols, 4, 2, 102342, 2023, Co-First Author
5. GAGAN, SATYASHREE; Khapuinamai, Agimanailiu; Yadavalli, Tejabhiram; Shukla, Deepak; Ruben, Joveeta Joseph; Bagga, Bhupesh; Expression of Heparan Sulfate degrading Enzyme: Heparanase in tears of patients diagnosed with HSV-1 keratitis, Investigative Ophthalmology & Visual Science, 64, 8, 2338-2338, 2023
6. Yadavalli, Tejabhiram; Madavaraju, Krishnaraju; Koganti, Raghuram; Singh, Sudhanshu Kumar; Ames, Joshua; Suryawanshi, Rahul; Patil, Chandrashekhar Devidas; Bhattacharya, Ilina; Shukla, Deepak; Use of a multi-omic approach to drug discovery for the treatment of HSV-1 infection, Investigative Ophthalmology & Visual Science, 64, 8, 5185-5185, 2023
7. Yadavalli, Tejabhiram; Singh, Sudhanshu Kumar; Date, Abhijit A; Shukla, Deepak; Tolerability, pharmacokinetics, and anti-herpetic activity of orally administered BX795, Biomedicine & Pharmacotherapy, 165, 115056, 2023
8. Yadavalli, Tejabhiram; Ames, Joshua; Wu, David; Ramirez, Benjamin; Bellamkonda, Navya; Shukla, Deepak; Safety, efficacy and delivery of multiple nucleoside analogs via drug encapsulated carbon (DECON) based sustained drug release platform, European Journal of Pharmaceutics and Biopharmaceutics, 173, 150-159, 2022
9. Bhattacharya, Ilina; Yadavalli, Tejabhiram*;; Wu, David; Shukla, Deepak; Plasma Membrane-Derived Liposomes Exhibit Robust Antiviral Activity against HSV-1, Viruses, 14, 4, 799, 2022, Co-First Author
10. Yadavalli, Tejabhiram; Sharma, Pankaj; Wu, David; Kapoor, Divya; Shukla, Deepak; CREB3 Plays an Important Role in HPSE-Facilitated HSV-1 Release in Human Corneal Epithelial Cells, Viruses, 14, 6, 1171, 2022
11. Koganti, Raghuram; Yadavalli, Tejabhiram*; Sutar, Yogesh; Mallick, Sudipta; Date, Abhijit; Shukla, Deepak; Topical phenylbutyrate antagonizes NF-κB signaling and resolves corneal inflammation, Iscience, 25, 12, 105682, 2022, Co-First Author
12. Patil Chandrashekhar D, Suryawanshi Rahul, Ames Joshua, Koganti Raghuram, Agelidis Alex, Kapoor Divya, Yadavalli Tejabhiram, Koujah Lulia, Tseng Henry C, Shukla Deepak, Intrinsic Antiviral Activity of Optineurin Prevents Hyperproliferation of a Primary Herpes Simplex Virus Type 2 Infection, The Journal of Immunology, 2022
13. Yadavalli Tejabhiram, Ames Joshua, Wu David, Ramirez Benjamin, Bellamkonda Navya, Shukla Deepak, Safety, efficacy and delivery of multiple nucleoside analogs via drug encapsulated carbon (DECON) based sustained drug release platform, European Journal of Pharmaceutics and Biopharmaceutics, 2022
14. Bhattacharya Ilina, Yadavalli Tejabhiram*, Wu David, Shukla Deepak, Plasma Membrane-Derived Liposomes Exhibit Robust Antiviral Activity against HSV-1, Viruses, 2022 (Co-First Author)
15. Yadavalli Tejabhiram, Sharma Pankaj, Wu David, Kapoor Divya, Shukla Deepak, CREB3 Plays an Important Role in HPSE-Facilitated HSV-1 Release in Human Corneal Epithelial Cells, Viruses, 2022
16. Agelidis Alex, Turturice Benjamin A, Suryawanshi Rahul K, Yadavalli Tejabhiram, Jaishankar Dinesh, Ames Joshua, Hopkins James, Koujah Lulia, Patil Chandrashekhar D, Hadigal Satvik R, Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival, JCI insight, 2021
17. Yadavalli Tejabhiram, Koganti Raghuram, Shukla Deepak, Infection-Induced Porcine Ex Vivo Corneal Wound Model to Study the Efficacy of Herpes Simplex Virus-1 Entry and Replication Inhibitors, Wound Regeneration, 2021
18. Chopra Pradeep, Joshi Apoorva, Wu Jiandong, Lu Weigang, Yadavalli Tejabhiram, Wolfert Margreet A, Shukla Deepak, Zaia Joseph, Boons Geert-Jan, The 3-O-sulfation of heparan sulfate modulates protein binding and lyase degradation, Proceedings of the National Academy of Sciences, 2021
19. Koujah Lulia, Allaham Mowafak, Patil Chandrashekhar D, Ames Joshua M, Suryawanshi Rahul K, Yadavalli Tejabhiram, Agelidis Alex, Mun Christine, Surenkhuu Bayasgalan, Jain Sandeep, Entry receptor bias in evolutionarily distant HSV-1 clinical strains drives divergent ocular and nervous system pathologies, The Ocular Surface, 2021
20. Madavaraju Krishnaraju, Yadavalli Tejabhiram*, Singh Sudhanshu Kumar, Qatanani Farreh, Shukla Deepak, Prophylactic treatment with BX795 blocks activation of AKT and its downstream targets to protect vaginal keratinocytes and vaginal epithelium from HSV-2 infection, Antiviral Research, 2021 (Co-First Author)
21. Ames Joshua, Yadavalli Tejabhiram, Suryawanshi Rahul, Hopkins James, Agelidis Alexander, Patil Chandrashekhar, Fredericks Brian, Tseng Henry, Valyi-Nagy Tibor, Shukla Deepak, OPTN is a host intrinsic restriction factor against neuroinvasive HSV-1 infection, Nature communications, 2021
22. Yadavalli Tejabhiram, Volety Ipsita, Shukla Deepak, Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals, JoVE (Journal of Visualized Experiments), 2021
23. Yadavalli Tejabhiram, Volety Ipsita, Shukla Deepak, Aptamers in virology—A Consolidated review of the most recent advancements in diagnosis and therapy, Pharmaceutics, 2021
24. Suryawanshi Rahul K, Patil Chandrashekhar D, Agelidis Alex, Koganti Raghuram, Ames Joshua M, Koujah Lulia, Yadavalli Tejabhiram, Madavaraju Krishnaraju, Shantz Lisa M, Shukla Deepak, mTORC2 confers neuroprotection and potentiates immunity during virus infection, Nature communications, 2021
25. Sutar Yogesh, Yadavalli Tejabhiram*, Paul Sagar Kumar, Mallick Sudipta, Koganti Raghuram, Chauhan Harsh, Date Abhijit A, Shukla Deepak, BX795-Organic Acid Coevaporates: Evaluation of Solid-State Characteristics, In Vitro Cytocompatibility and In Vitro Activity against HSV-1 and HSV-2, Pharmaceutics, 2021 (Co-First Author)
26. Yadavalli Tejabhiram, Suryawanshi Rahul, Ali Marwan, Iqbal Aqsa, Koganti Raghuram, Ames Joshua, Aakalu Vinay Kumar, Shukla Deepak, Prior inhibition of AKT phosphorylation by BX795 can define a safer strategy to prevent herpes simplex virus-1 infection of the eye, The ocular surface, 2020
27. Hadigal Satvik, Koganti Raghuram, Yadavalli Tejabhiram, Agelidis Alex, Suryawanshi Rahul, Shukla Deepak, Heparanase-regulated syndecan-1 shedding facilitates herpes simplex virus 1 egress, Journal of Virology, 2020
28. Suryawanshi Rahul K, Koujah Lulia, Patil Chandrashekhar D, Ames Joshua M, Agelidis Alex, Yadavalli Tejabhiram, Patil Satish V, Shukla Deepak, Bacterial pigment prodigiosin demonstrates a unique antiherpesvirus activity that is mediated through inhibition of prosurvival signal transducers, Journal of virology, 2020
29. Iqbal Aqsa, Suryawanshi Rahul, Yadavalli Tejabhiram, Volety Ipsita, Shukla Deepak, BX795 demonstrates potent antiviral benefits against herpes simplex Virus-1 infection of human cell lines, Antiviral research, 2020
30. Hopkins James, Yadavalli Tejabhiram*, Suryawanshi Rahul, Qatanani Farreh, Volety Ipsita, Koganti Ram, Iqbal Aqsa, Shukla Deepak, In vitro and in vivo activity, tolerability, and mechanism of action of BX795 as an antiviral against herpes simplex virus 2 genital infection, Antimicrobial agents and chemotherapy, 2020 (Co-First Author)
31. Suryawanshi Rahul K, Patil Chandrashekhar D, Agelidis Alex, Koganti Raghuram, Ames Joshua M, Koujah Lulia, Yadavalli Tejabhiram, Madavarju Krishnaraju, Shantz Lisa M, Shukla Deepak, mTORC2 combats cellular stress and potentiates immunity during viral infection, bioRxiv, 2020
32. Yadavalli Tejabhiram, Mallick Sudipta, Patel Pratikkumar, Koganti Raghuram, Shukla Deepak, Date Abhijit A, Pharmaceutically acceptable carboxylic acid-terminated polymers show activity and selectivity against HSV-1 and HSV-2 and synergy with antiviral drugs, ACS infectious diseases, 2020
33. Yadavalli Tejabhiram, Suryawanshi Rahul, Koganti Raghuram, Hopkins James, Ames Joshua, Koujah Lulia, Iqbal Aqsa, Madavaraju Krishnaraju, Agelidis Alex, Shukla Deepak, Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing, Science advances, 2020
34. Gopinath Venkatraman, Priyadarshini S, MubarakAli Davoodbasha, Loke Mun Fai, Thajuddin Nooruddin, Alharbi Naiyf S, Yadavalli Tejabhiram, Alagiri Mani, Vadivelu Jamuuna, Anti-Helicobacter pylori, cytotoxicity and catalytic activity of biosynthesized gold nanoparticles: multifaceted application, Arabian journal of chemistry, 2019
35. Agelidis Alex, Koujah Lulia, Suryawanshi Rahul, Yadavalli Tejabhiram, Mishra Yogendra Kumar, Adelung Rainer, Shukla Deepak, An intra-vaginal zinc oxide tetrapod nanoparticles (ZOTEN) and genital herpesvirus cocktail can provide a novel platform for live virus vaccine, Frontiers in immunology, 2019
36. Yadavalli Tejabhiram, Ames Joshua, Agelidis Alex, Suryawanshi Rahul, Jaishankar Dinesh, Hopkins James, Thakkar Neel, Koujah Lulia, Shukla Deepak, Drug-encapsulated carbon (DECON): A novel platform for enhanced drug delivery, Science advances, 2019
37. Jaishankar Dinesh, Yakoub Abraam M, Yadavalli Tejabhiram, Agelidis Alex, Thakkar Neel, Hadigal Satvik, Ames Joshua, Shukla Deepak, An off-target effect of BX795 blocks herpes simplex virus type 1 infection of the eye, Science translational medicine, 2018
38. Naqvi Afsar R, Seal Alexandra, Shango Jennifer, Brambila Maria F, Martinez Gloria, Chapa Gabriela, Hasan Shirin, Yadavalli Tejabhiram, Jaishankar Dinesh, Shukla Deepak, Herpesvirus-encoded microRNAs detected in human gingiva alter host cell transcriptome and regulate viral infection, Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms, 2018
39. Hopkins James, Yadavalli Tejabhiram, Agelidis Alex M, Shukla Deepak, Host enzymes heparanase and cathepsin L promote herpes simplex virus 2 release from cells, Journal of Virology, 2018
40. Yadavalli Tejabhiram, Raja Pradeep, Ramaswamy Shivaraman, Chandrasekharan Gopalakrishnan, Chennakesavulu Ramasamy, Proton Relaxivity and Magnetic Hyperthermia Evaluation of Gadolinium Doped Nickel Ferrite Nanoparticles as Potential Theranostic Agents, Journal of Nanoscience and Nanotechnology, 2017
41. Raja Pradeep, Yadavalli Tejabhiram, Ravi Diwakar, Therese Helen Annal, Ramasamy C, Hayakawa Y, Synthesis and magnetic properties of gadolinium substituted zinc ferrites, Materials Letters, 2017
42. Thakkar Neel, Jaishankar Dinesh, Agelidis Alex, Yadavalli Tejabhiram, Mangano Kyle, Patel Shrey, Tekin Sati Zeynep, Shukla Deepak, Cultured corneas show dendritic spread and restrict herpes simplex virus infection that is not observed with cultured corneal cells, Scientific reports, 2017
43. Duggal Neil, Jaishankar Dinesh, Yadavalli Tejabhiram, Hadigal Satvik, Mishra Yogendra Kumar, Adelung Rainer, Shukla Deepak, Zinc oxide tetrapods inhibit herpes simplex virus infection of cultured corneas, Molecular vision, 2017
44. Krishna Prashanth Gopala, Ananthaswamy Prashanth Paduvarahalli, Trivedi Priyanka, Chaturvedi Vinita, Mutta Nagabhushana Bhangi, Sannaiah Ananda, Erra Amani, Yadavalli Tejabhiram, Antitubercular activity of ZnO nanoparticles prepared by solution combustion synthesis using lemon juice as bio-fuel, Materials science and Engineering: C, 2017
45. Yadavalli Tejabhiram, Agelidis Alex, Jaishankar Dinesh, Mangano Kyle, Thakkar Neel, Penmetcha Kumar, Shukla Deepak, Targeting herpes simplex virus-1 gD by a DNA aptamer can be an effective new strategy to curb viral infection, Molecular Therapy-Nucleic Acids, 2017
46. Krishna Prashanth Gopala, Ananthaswamy Prashanth Paduvarahalli, Yadavalli Tejabhiram, Mutta Nagabhushana Bhangi, Sannaiah Ananda, Shivanna Yogisha, ZnO nanopellets have selective anticancer activity, Materials Science and Engineering: C, 2016
47. Tejabhiram Yadavalli, Hardik Jain, Gopalakrishnan Chandrasekharan, Ramasamy Chennakesavulu, Magnetic hyperthermia heating of cobalt ferrite nanoparticles prepared by low temperature ferrous sulfate based method, AIP Advances, 2016
48. Yadavalli Tejabhiram, Ramasamy Shivaraman, Chandrasekaran Gopalakrishnan, Michael Isaac, Therese Helen Annal, Chennakesavulu Ramasamy, Dual responsive PNIPAM–chitosan targeted magnetic nanopolymers for targeted drug delivery, Journal of magnetism and Magnetic Materials, 2015
49. Yadavalli Tejabhiram, Raja Pradeep, Therese Helen Annal, Ramasamy C., Ferrous sulfate based low temperature synthesis and magnetic properties of nickel ferrite nanoparticles, Materials Research Bulletin, 2014
50. Mahapatra Ojas, Ramaswamy Shivaraman, Nune Satya Vijaya Kumar, Yadavalli Tejabhiram, Gopalakrishnan Chandrashekaran; Corn flake-like morphology of iron nanoparticles and its antibacterial property, The Journal of General and Applied Microbiology, 2011
REVIEW ARTICLES:
1. Yadavalli, Tejabhiram; Patil, Chandrashekhar; Jaishankar, Dinesh; Suryawanshi, Rahul; Ocular infection of herpes: Immunology, pathogenesis, and interventions, Frontiers in Microbiology, 13, 986859, 2022
2. Madavaraju Krishnaraju, Koganti Raghuram, Volety Ipsita, Yadavalli Tejabhiram, Shukla Deepak, Herpes simplex virus cell entry mechanisms: An update, Frontiers in Cellular and Infection Microbiology, 2021
3. Koganti Raghuram, Yadavalli Tejabhiram, Naqvi Raza Ali, Shukla Deepak, Naqvi Afsar R, Pathobiology and treatment of viral keratitis, Experimental Eye Research, 2021
4. Wu David, Koganti Raghuram, Lambe Upendra P, Yadavalli Tejabhiram, Nandi Shyam S, Shukla Deepak, Vaccines and therapies in development for SARS-CoV-2 infections, Journal of clinical medicine, 2020
5. Koganti Raghuram, Yadavalli Tejabhiram, Shukla Deepak, Current and emerging therapies for ocular herpes simplex virus type-1 infections, Microorganisms, 2019
6. Munro Monique, Yadavalli Tejabhiram, Fonteh Cheryl, Arfeen Safa, Lobo-Chan Ann-Marie, Cytomegalovirus retinitis in HIV and non-HIV individuals, Microorganisms, 2019
7. Yadavalli Tejabhiram, Shukla Deepak, Role of metal and metal oxide nanoparticles as diagnostic and therapeutic tools for highly prevalent viral infections, Nanomedicine: Nanotechnology, Biology and Medicine, 2017
8. Thakkar Neel, Yadavalli Tejabhiram, Jaishankar Dinesh, Shukla Deepak, Emerging roles of heparanase in viral pathogenesis, Pathogens, 2017
9. Yadavalli Tejabhiram, Shukla Deepak, Could zinc oxide tetrapod nanoparticles be used as an effective immunotherapy against HSV-2?, Nanomedicine, 2016